Ireland snapped a four-match losing streak against England with a commanding 32-18 Super Saturday victory in Dublin.
Keith Earls and Jack Conan scored first-half tries for the Men in Green, while Johnny Sexton added 22 points from the kicking tee.
Bundee Aki’s red card mid-way through the second half opened the door for England, who scored tries from Ben Youngs and Jonny May.
But they were too far back to stage a comeback and Ireland saw it out, their third win in a row ensuring they will finish above England in the table.