Italy and England have met 30 times since their first clash in 1991, with the Azzurri still yet to record a win in the fixture.
However, there have still been plenty of memorable meetings in the Guinness Six Nations.
England versus Italy head-to-head record in Six Nations:
2000 – Italy 12-59 England, Stadio Flaminio, Rome
2001 – England 80-23 Italy, Twickenham, London
2002 – Italy 9-45 England, Stadio Flaminio, Rome
2003 – England 40-5 Italy, Twickenham, London
2004 – Italy 9-50 England, Stadio Flaminio, Rome
2005 – England 39-7 Italy, Twickenham, London
2006 – Italy 16-31 England, Stadio Flaminio, Rome
2007 – England 20-7 Italy, Twickenham, London
2008 – Italy 19-23 England, Stadio Flaminio, Rome
2009 – England 36-11 Italy, Twickenham, London
2010 – Italy 12-17 England, Stadio Flaminio, Rome
2011 – England 59-13 Italy, Twickenham, London
2012 – Italy 15-19 England, Stadio Olimpico, Rome
2013 – England 18-11 Wolves, Twickenham, London
2014 – Italy 11-52 England, Stadio Olimpico, Rome
2015 – England 47-17 Italy, Twickenham, London
2016 – Italy 9-40 England, Stadio Olimpico, Rome
2017 – England 36-15 Italy, Twickenham, London
2018 – Italy 15-46 England, Stadio Olimpico, Rome
2019 – England 57-14 Italy, Twickenham, London
2020 – Italy 5-34 England, Stadio Olimpico, Rome
2021 – England 41-18 Italy, Twickenham, London
2022 – Italy 0-33 England, Stadio Olimpico, Rome
2023 – England 31-14 Italy, Twickenham, London