Italy are fourth in the table currently but could leapfrog France if they beat Wales, and England secure the title with a win in Pau.
Massimo Brunello’s team have been excellent since losing to England in Round 1. They were within seven minutes of inflicting the first home defeat on Ireland U20 since 2018 in Round 2, and have also beaten France and Scotland.
Against the latter, they overturned a 14-7 half-time deficit by scoring 40 unanswered points in the second half.
This weekend, Brunello has made seven changes, such is his confidence in this group of players and his determination to create as deep a talent pool as possible.
Meanwhile, Wales are chasing a second win of what has been a tough campaign. In contrast to Italy, they made a flying start to the Championship, beating Scotland 37-29 in Round 1, but have since lost to England, Ireland and France.
Italy won this fixture last season, emerging 29-25 winners in Treviso.
WHERE TO WATCH
UK viewers can watch the match on BBC iPlayer and on Welsh language channel S4C.
TEAM NEWS
Wales have made four changes in the backs plus two positional changes.
Huw Anderson moves from full-back to wing to accommodate Matty Young in the number 15 jersey and Macs Page moves from outside centre to inside centre with Elijah Evans starting in the number 13 jersey.
Rhodri Lewis gets his first start of the campaign at scrum half with Ieuan Davies dropping down to the bench.
In the pack Evan Wood gets a first start at hooker in place of Harry Thomas while Jonny Green returns to the second row at the expense of Osian Thomas who drops to the bench.
Harry Beddall will captain the side from openside flanker after injury to Harri Ackerman has ended his championship prematurely.
Italy head coach Massimo Brunello has made seven changes to his team, as he continues to build as deep a squad as possible.
Centre Federico Zanandrea, winger Lorenzo Elettri and scrum-half Lorenzo Casilio come into the back line, while lock Samuele Mirenzi packs down behind a new front row of loosehead Federico Pisani, hooker Valerio Siciliano and tighthead Marcos Gallorini.
WHAT THEY SAID
Wales head coach Richard Whiffin said: "We’ve come to the end of the campaign, and we’ve got quite a few boys banged up.
"This game is also an opportunity to see some other players under a pressure situation. It’s a chance for those selected to put their hands up for selection in the World Cup later this year.
"We’ve shown elements of strong attack, strong defence and strong set piece and decent collision throughout the tournament but only sporadically and not simultaneously so that has been the message this week to the boys.
“We have shown good aspects to our game, but we have to be able to deliver all those elements together consistently."
TEAMS
Wales U20s team: 15 Matty Young, 14 Huw Anderson, 13 Elijah Evans, 12 Macs Page, 11 Aidan Boschoff, 10 Harri Wilde, 9 Rhodri Lewis, 1 Josh Morse, 2 Evan Wood, 3 Kian Hire, 4 Jonny Green, 5 Nick Thomas, 6 Lucas de la Rua, 7 Harry Beddall (c), 8 Morgan Morse
Replacements: 16 Harry Thomas, 17 Jordan Morris, 18 Sam Scott, 19 Gethyn Cannon, 20 Osian Thomas, 21 Ieuan Davies, 22 Elis Price, 23 Kodi Stone
Italy U20s team: 15 Mirko Belloni, 14 Marco Scalabrin, 13 Federico Zanandrea, 12 Nicola Bozzo, 11 Lorenzo Elettri, 10 Martino Pucciariello, 9 Lorenzo Casilio, 8 Jacopo Botturi (capitano), 7 Luca Bellucci, 6 Cesare Zucconi, 5 Piero Gritti, 4 Samuele Mirenzi, 3 Marcos Gallorini, 2 Valerio Siciliano, 1 Federico Pisani
Replacements: 16 Nicholas Gasperini, 17 Sergio Pelliccioli, 18 Davide Ascari, 19 Giacomo Milano, 20 Mattia Midena, 21 Mattia Jimenez, 22 Francesco Imberti, 23 Patrick De Villiers
