Pauline Bourdon Sansus' try gave the hosts an ideal start and the influential scrum-half later set up Marine Ménager for the second before half-time.
The power of the home pack began to tell in the second half, with giant lock Madoussou Fall adding her name to the scoresheet before Agathe Sochat secured the bonus point following a dominant rolling maul.
Elisa Riffoneau also benefitted from a strong catch-and-drive routine either side of tries from Aoife Wafer and Aoife Dalton, who dotted down inside the final 10 minutes to give Ireland plenty of positives on which to build for the remainder of their campaign.
BOURDON SANSUS SETS THE TONE
The 2024 Championship was less than three minutes old when it was graced with its first try.
An early Irish indiscretion at the breakdown led to Lina Queyroi finding touch inside the visiting 22 and France made the early territory pay as Bourdon Sansus collected the ball at the back of the maul and darted through a gap to open the scoring.
Queyroi added the extras and France remained on the front foot in the early stages without adding to their lead, with Les Bleues met by some fierce Irish defence.
Scott Bemand's side paid for some early handling errors in an attacking sense but got themselves on the board in the 14th minute, Nicole Fowley slotting through a three-pointer when her side's pack earned a penalty at scrum time.
Ireland had their first opportunity to build inside the French 22 shortly afterwards but were unable to make it count as the lineout was spilled, which they almost paid for swiftly only for Charlotte Escudero's bulldozing run to be halted when the flanker was held up over the line.
Romane Ménager was later thwarted a couple of metres out but France's pressure soon told with eight minutes of the first half remaining.
Bourdon Sansus was the architect on this occasion, a neat pop back inside finding a rampaging Marine Ménager, who beat the final defender with a step inside and finished under the posts.
Queyroi converted before slotting over a penalty to hand France a 17-3 lead at the break.
FRENCH PACK SEIZE CONTROL
France started the second half as they ended the first, applying immediate pressure to the Irish line.
Following a lineout in the corner, several forwards had a crack at penetrating the Irish defence and eventually the dam broke when Fall powered through under the posts.
They thought they had the bonus point in the bag when 18-year-old debutant Kelly Arbey broke clear to sprint in down the left, only for replays to show Nassira Kondé's offload from the floor to Morgane Bourgeois was forward.
Les Bleues did not have to wait long for their fourth score, however, and it came from a tried and tested source.
A catch-and-drive saw the pack gather momentum and hooker Sochat benefitted to dot down, with Queyroi continuing her successful afternoon off the tee with the conversion.
Ireland kept battling and were rewarded for their efforts with a deserved try courtesy of the impressive 21-year-old back rower Wafer, who burrowed over from close range for her side's first score of the afternoon.
France hit back with another unstoppable lineout, the maul this time finished by replacement hooker Riffoneau, but Ireland had the final word as Dalton successfully put pressure on Lina Tuy after a loose pass and seized on the loose ball over the line.
