The match is a crucial play-off clash for the new global WXV tournament, the winner of which will qualify for WXV2 in South Africa. The runner-up will compete in WXV3 in Dubai. Wales beat Italy 22-20 in the final game of the Guinness Women’s Six Nations at the end of April, in front of a record 10,592 crowd at the Principality Stadium.
The Arms Park has become the spiritual home of Hannah Jones’ Wales side, having set the previous record crowd of 8,500 at the venue, followed there by record crowds against Scotland and France during this year's Championship.
Wales will face a Spain side that won the last Test match between the two sides 29-5 back in November 2019, while Las Leonas won their most recent Test match when they beat Sweden 53-0 in the European Championship.
Wales Head coach Ioan Cunningham called the meeting with Spain in the capital a "major Test match" for his side, adding: "The squad, coaches and staff know how important this game is for all of us.
"Our victory against Italy in the Six Nations provides us with a platform to build on and to move forward with the 2025 World Cup in England still very much the focus for the team.
"One of the goals we have set ourselves is to build the depth and competition for places in the squad and we did that with six new caps getting a taste of Test match rugby during our last campaign.
"Spain have been one of the traditional benchmarks in our game and will travel to Wales full of confidence after their recent performances. We know they will be determined to make a statement against us at home in front of our own supporters at Cardiff Arms Park."
Supporters will get the chance to enjoy two games for the price of one, with the crucial Test match being followed by a Classic Lions v Armed Forces Legends charity game at the Arms Park. Mike Phillips is set to feature for the Lions team, among other recognisable names.