Gwenllian Pyrs is joined in the front row by hooker Carys Phillips and Donna Rose at tighthead prop.
Georgia Evans partners Abbie Fleming in the engine room, while Kate Williams is selected alongside vice-captain Alex Callender and Bethan Lewis in the backrow.
Sian Jones (pictured), who made her debut off the bench against the Scots, starts her first Test match for her country and partners fly half Lleucu George at half back.
Carys Cox is selected on the wing with the experienced Jasmine Joyce on the other wing and Jenny Hesketh at full back, while the experienced centre Kerin Lake partners skipper Jones in the midfield.
Wales team to face England
15 Jenny Hesketh; 14 Jasmine Joyce; 13 Hannah Jones (captain), 12 Kerin Lake; 11 Carys Cox; 10 Lleucu George, 9 Sian Jones; 1 Gwenllian Pyrs, 2 Carys Phillips, 3 Donna Rose; 4 Abbie Fleming, 5 Georgia Evans; 6 Kate Williams, 7 Alex Callender (vice-captain), 8 Bethan Lewis
Replacements 16 Kelsey Jones, 17 Abby Constable, 18 Sisilia Tuipulotu, 19 Natalia John, 20 Alisha Butchers, 21 Keira Bevan, 22 Kayleigh Powell, 23 Nel Metcalfe
